UK – Amgen’s Blincyto recommended by NICE for new adult leukaemia indication

Amgen’s Blincyto (blinatumomab) has been recommended by the National Institute for Health and Care Excellence (NICE) to treat certain cases of acute lymphoblastic leukaemia (ALL).

The health technology assessment agency has recommended in final draft guidance that the immunotherapy be used on the NHS in combination with chemotherapy to treat adults with Philadelphia chromosome-negative CD19-positive B-cell precursor ALL in the consolidation phase, a phase of frontline treatment for ALL which is aimed at killing any remaining leukaemia cells.

Eligible patients must also be minimal residual disease-negative, meaning they have responded well to initial therapy and have no detectable cancer cells…