UK – NICE recommendation for new Alexion PNH treatment

Danicopan shown to improve haemoglobin levels and reduce anaemia

Alexion, AstraZeneca Rare Disease, announced that the National Institute for Health and Care Excellence (NICE) has given a positive recommendation for Voydeya (danicopan).

This first-in-class, oral Factor D inhibitor can now be used as an add-on to ravulizumab or eculizumab for treating paroxysmal nocturnal haemoglobinuria (PNH) in adults with residual haemolytic anaemia, provided they have clinically significant extravascular haemolysis (EVH) while on treatment with a complement component 5 inhibitor (C5 inhibitor)…