A new targeted drug combination treatment, described as a ‘step-change in care’ for children and young people with an aggressive form of brain cancer, has today (Wednesday, 24 April) been recommended by NICE.
Dabrafenib (also known as Finlee) in combination with trametinib (also known as Spexotras, both made by Novartis) is being recommended in final draft guidance for treating BRAF V600E mutation-positive glioma.
Gliomas are the most common type of brain cancer in children and young people. They develop from the glial cells that support the nerve cells of the brain and spinal cord. BRAF is a specific gene mutation which causes the body to make faulty proteins, which in turn cause tumours to develop in the brain…
