UK – AstraZeneca/Merck’s Lynparza combination recommended by NICE for advanced ovarian cancer

AstraZeneca (AZ) and Merck’s – known as MSD outside the US and Canada – Lynparza (olaparib) has been recommended by the National Institute for Health and Care Excellence (NICE) as part of a combination treatment for a subset of ovarian cancer patients.

The drug has been specifically recommended for NHS use alongside Genentech’s Avastin (bevacizumab) as a maintenance treatment in adults with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer, whose disease is associated with homologous recombination deficiency (HRD)-positive status.

Eligible patients will also need to be in complete or partial response to first-line platinum-based chemotherapy…